CIII allows people who have tried at least two oral antidepressants to use the spray on its own – without the need for more ...

The nasal spray Spravato, which is made from the drug esketamine, had been approved in 2019 for patients who failed to ...

though only a molecule of ketamine called esketamine that’s used in smaller doses is active in Spravato. Ketamine is also sometimes distributed illegally, mostly after being stolen from ...

Esketamine, which Spravato is derived from, is a molecule related to the anesthetic ketamine. According to the manufacturer, Spravato works by targeting glutamate, which is the brain's most ...